Evidence based

| 6 min read

The Carnivore Code AMA (Ask Me Anything) from Ben Greenfield Episode!

The second edition of The Carnivore Code is now live in print, ebook, and audiobook formats!  www.Thecarnivorecodebook.com to order! 

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In this AMA episode I answer questions from Ben Greenfield about my book, The Carnivore Code. It’s a deep dive into much of the science of an animal-based way eating. Prepare to learn a ton!

Time Stamps:

8:03 Carnivore diet background, framework

18:25 Is there a magic ratio of fat to protein we should aim for? What is rabbit starvation?

25:53 A Review of Issues of Dietary Protein Intake in Humans

33:01. Is the decline in height and health fully attributable to plant agriculture or could it be due to industrialization?

38:43 Why do present day hunter-gatherers have no access to wild game?

42:54 How do we know that our high stomach acidity was driven by the consumption of animals? 

45:09 The Evolution of Stomach Acidity and Its Relevance to the Human Microbiome https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134116

50:51 How do herbivores detoxify plant toxins?

56:34 Coevolution of poisonous plants and large herbivores on rangelands 


1:02:09 What are the studies of isothiocyanates in humans?

1:04:39  Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892312/

1:07:03  Why molecular hormesis is bad news

1:14:42  Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060837/ 

1:18:03 Green tea extract only affects markers of oxidative status postprandially: Lasting antioxidant effect of flavonoid-free diet   https://www.researchgate.net/publication/11310865_Green_tea_extract_only_affects_markers_of_oxidative_status_postprandially_Lasting_antioxidant_effect_of_flavonoid-free_diet

1:20:08 Uric acid and glutathione levels during short-term whole body cold exposure https://pubmed.ncbi.nlm.nih.gov/8063192/

1:21:14 Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans https://www.nature.com/articles/ncomms14337

1:22:58  Is there an acceptable dose of isoflavones? 

1:23:53  Goitrogenic and Estrogenic Activity of Soy Isoflavones https://www.jstor.org/stable/3455387?seq=1

1:25:32 Isoflavones: estrogenic activity, biological effect and bioavailability  https://www.researchgate.net/publication/233538635_Isoflavones_Estrogenic_activity_biological_effect_and_bioavailability

1:26:48 Low Dietary Soy Isoflavonoids Increase Hippocampal Spine Synapse Density in Ovariectomized Rats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330193/

1:29:56 Is resveratrol really something we should avoid?

1:31:09  David Sinclair’s work on Resveratrol https://www.ncbi.nlm.nih.gov/pmc/?term=sinclair%2C+david+resveratrol

1:32:02 Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4‐month randomised trial in middle‐aged men https://pubmed.ncbi.nlm.nih.gov/25939591/#:~:text=Conclusion%3A%20In%20this%20population%20of,PSA%2C%20testosterone%2C%20free%20testosterone%2C

1:33:03 Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease https://pubmed.ncbi.nlm.nih.gov/26784973/

1:33:53 Prooxidant activity of research all in the presence of copper ions: mutagenicity in plasmid DNA https://www.sciencedirect.com/science/article/abs/pii/S0378427405001190?via%3Dihub

1:35:17 Resveratrol levels and all cause mortality in older community-dwelling adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346286/

1:36:16  resveratrol improves vascular function and mitochondrial number but not in glucose metabolism in older adults  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861959/

1:37:29  What are event-related potentials and how are they measured?

1:37:29 Food processing and emotion regulation in vegetarians and omnivores: an event-related potential investigation  https://www.sciencedirect.com/science/article/abs/pii/S0195666319300595?via%3Dihub

1:40:54 What really drives insulin resistance?

1:48:37  Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164353/

1:51:02 dietary stearic acid regulates mitochondria in vivo in humans  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081440/

1:53:52  What would you change in your diet if you had cancer? 

1:56:03 Halted Progression of Soft Palate Cancer in a Patient Treated with the Paleolithic Ketogenic Diet Alone: A 20-months Follow-up http://pubs.sciepub.com/ajmcr/4/8/8/

1:57:29 Complete Cessation of Recurrent Cervical Intraepithelial Neoplasia (CIN) by the Paleolithic Ketogenic Diet: A Case Report


1:58:47  Are there any studies looking at telomere length in plant vs animal food diets? 

2:00:10 Processed meat, but not unprocessed red meat, is inversely associated with leukocyte telomere length in the Strongheart family study  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037876/

2:00:41 Epigenetic clock analysis of diet, exercise, education, and lifestyle factors https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361673/

2:00:54  Effects of diet on telomere length: systematic review and meta-analysishttps://www.karger.com/?DOI=10.1159/000486586

2:02:00  Dietary intervention modifies DNA methylation age assessed by epigenetic clock  https://doi.org/10.1002/mnfr.201800092

2:04:21  Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/137.2.363 

2:07:40 Would eating fruit without the seeds be a healthy choice? 

2:08:07  Why does CarnivoreMD prefer unrendered fat?

2:00:37  Is dietary saturated fat something to be concerned about?

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